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Three-Dimensional Electron Microscopy of Macromolecular Assemblies: Visualization of Biological Molecules in Their Native State
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About the Author
Joachim Frank is an Investigator at the Howard Hughes Medical Institute. He is also Professor of Biomedical Sciences and Adjunct Professor of Biology at the State University of New York at Albany, Adjunct Professor of Biochemistry and Molecular Biophysics at Columbia University, Research Professor of Cell Biology at New York State University Medical School, and head of the Laboratory of Computational Biology and Macromolecular Imaging at Health Research, Inc., the Wadsworth Center.
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Product details
Paperback: 432 pages
Publisher: Oxford University Press; 2 edition (February 2, 2006)
Language: English
ISBN-10: 0195182189
ISBN-13: 978-0195182187
Product Dimensions:
9.1 x 0.9 x 6 inches
Shipping Weight: 1.6 pounds (View shipping rates and policies)
Average Customer Review:
5.0 out of 5 stars
2 customer reviews
Amazon Best Sellers Rank:
#1,524,425 in Books (See Top 100 in Books)
This concise and easy to read book is essentialy a crash course in single particle reconstruction by electron microscopy. It isn't exactly a how-to manual, more an overview of how the whole process works. Thus, it is useful not only to someone who wants to learn how to do this, but also to those who might be interested in deciding if this technique would be useful to them. And actually, the whole topic is sufficiently cool that I would recommend the book even to people who know they will never use this technique, just because its fun to read about it. The book is clearly written and doesn't assume alot of prior knowledge. A basic undergrad education in math would be enough to handle the equations.
The author is one of the inventors of this technique. And he also won the Nobel prize in Chemistry in 2017 because of his contribution in Cryo-EM. So it absolutely worth to read it.
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